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  1. Around 30% of people with depression have what’s known as treatment-resistant depression, meaning multiple kinds of medication or therapy have failed to improve their symptoms. And for up to two-thirds of people with depression, treatment fails to fully reverse their symptoms to healthy levels.

  2. Symptoms of depression can include feelings of hopelessness, anger, irritability, tiredness, and difficulty concentrating. A doctor may diagnose depression if a person experiences symptoms for...

  3. The six biotypes of depression the authors found include one characterized by hyperactivity in cognitive regions, which was associated with more anxiety, negative bias, threat dysregulation and ...

  4. This narrative review uses data from network meta-analyses and systematic reviews to explore the prevalence, diagnosis, and treatment of major depression

  5. Depression Signs and Symptoms Recognizing and Understanding Depression Are you depressed? Here are some of the signs of depression to look for—and how symptoms can vary according to your age, gender, and other factors.

  6. Though depression is common, it is a serious mental health condition that can impact how you feel, what you eat, and how you sleep, work, and more. Read about depression and its symptoms, ways to prevent it, and when to seek treatment.

  7. Understanding the different types and causes of depression can help you find the most effective treatment—whether you’re dealing with clinical depression, atypical, treatment-resistant, or high-functioning depression.

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