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Mitosis Mitosis (karyokinesis) occurs during the M phase of the cell cycle, in which duplicated DNA is organized for equipartition-ing.21,42 The DNA of any complete genome is exceedingly longer than the cell diameter (in humans, almost 2 meters, with cells less than 1/100 000th of that size), translating to a hercu-
1 de dic. de 2009 · Atypical mitoses: morphology and classification. Harold Tvedten, Harold Tvedten. Swedish University of Agricultural Sciences. Search for more papers by this author. Harold Tvedten, Harold Tvedten. Swedish University of Agricultural Sciences. Search for more papers by this author.
29 de dic. de 2020 · El-Alfy M, Leblond C. Long duration of mitosis and consequences for the cell cycle concept, as seen in the isthmal cells of the mouse pyloric antrum. II. Duration of mitotic phases and cycle stages, and their relation to one another. Cell Tissue Kinet. 1987;20(2):215–226.
20 de dic. de 2023 · Cell division through mitosis (microscopically visible as mitotic figures, MFs) is a highly regulated process. However, neoplastic cells may exhibit errors in chromosome segregation (microscopically visible as atypical mitotic figures, AMFs) resulting in aberrant chromosome structures. AMFs have been shown to be of prognostic relevance for some neoplasms in humans but not in animals.
Dispersed mitosis: is a type of atypical mitosis where the cell is enlarged and the chromosomes are dispersed, evenly distributed and non-clumped; it shows no specific configuration (figure 3H,h).40 55. This type of mitosis similar to some other forms of atypical mitosis should be differentiated from apoptotic and karyorrhectic nuclei.
19 de jun. de 2014 · Defects of mitosis result in various nuclear abnormalities, namely, micronuclei, binucleation, ... constitute an early step in the tumorigenic transformation of stem and progenitor cells and result in formation of atypical/multipolar mitosis (According to studies done by Arnold (1879), von Hansemann (1890), Mendelsohn).
1 de may. de 2022 · Atypical mitosis is considered a feature of malignancy, however, its significance in breast cancer (BC) remains elusive. Here, we aimed to assess the clinical value of atypical mitoses in BC and ...
