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  1. 22 de abr. de 2024 · Therefore, exploring the inflammatory markers of physical frailty and cognitive impairment is crucial to fully understanding these mechanisms and establishing a substantial link between these two disorders. Notably, few studies have focused on exploring inflammatory markers in both physical frailty and cognitive impairment, posing a major ...

  2. 26 de nov. de 2020 · Cognitive frailty is an emerging concept and condition of reduced neuropsychological reserve where physical frailty and mild cognitive impairment ... Cognitive and physical markers of prodromal dementia: A 12-year-long population study. J. Alzheimers Assoc. 16 153–161. 10.1002/alz.12002 ...

  3. 19 de sept. de 2014 · Frailty most closely correlated with functional impairment, r = −0.80, p < 0.001. Conclusion. The majority of patients in this community sample were perceived to be low risk for adverse outcomes. Frailty, cognitive impairment and functional status were markers of perceived risk.

  4. Frailty markers included 5 of 6 markers specifically related to cognition and 6 of 12 markers associated with hypomobility. These overlapping sets of markers included ... While a total of 22 metabolites were identified relative to frailty, cognitive impairment, and hypomobility, levels of 16 compounds—acetyl-carnosine, ET, S-methyl-ET, OA ...

  5. 6 de ene. de 2021 · Cognitive frailty has been linked to a higher risk of dementia, and is often seen as a precursor to Alzheimer’s disease (Buchman et al., 2007; Kojima et al., 2016; Panza et al., 2006; Shimada et al., 2018; Wang et al., 2017). In addition, cognitive frailty, irrespective of comorbid physical frailty, is associated with

  6. Neurophysiological and Brain Structural Markers of Cognitive Frailty Differ from Alzheimer’s Disease.pdf Available via license: CC BY 4.0 Content may be subject to copyright.

  7. 1 de mar. de 2019 · Cognitive frailty as the link between MCI and motor efficiency; early motor impairments: TMT-A & TMT-B, ... Motor tasks may not only be reliable markers of physical frailty but also useful measures of the impact of the cognitive dedifferentiation process on highly automatized motor behaviors [39].