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11 de nov. de 1996 · Direct coupling between water and Na + /glucose cotransport can be demonstrated in experiments where sugar transport is rapidly altered by voltage. Fig. 4 shows an experiment where Na + /glucose cotransport is increased 4-fold (from 280 to 950 nA) by stepping the membrane voltage from 0 to −100 mV.
1 de ene. de 2001 · Its action is terminated by removal from the synaptic cleft mostly via Na(+)-dependent uptake systems located on both neurons and astrocytes. Here we report that glutamate, in addition to its receptor-mediated actions on neuronal excitability, stimulates glycolysis--i.e., glucose utilization and lactate production--in astrocytes.
8 de dic. de 2021 · SGLT1, the first member of the large sodium–solute symporter (SSS) family 2 to be identified, is a high-affinity, low-capacity glucose transporter with an apparent 2 Na + :1 sugar coupling ...
26 de ago. de 2020 · Given a tight coupling between substrate and H + transport, the free energy stored in the electrochemical proton gradient allows for a more than 1,000-fold accumulation of the substrate . Animals evolved the Na + /K + ATPase for the maintenance of ionic gradients across the plasma membrane [49, 151, 152].
25 de oct. de 1994 · Its action is terminated by removal from the synaptic cleft mostly via Na(+)-dependent uptake systems located on both neurons and astrocytes. Here we report that glutamate, in addition to its receptor-mediated actions on neuronal excitability, stimulates glycolysis--i.e., glucose utilization and lactate production--in astrocytes.
12 de nov. de 1996 · Water is transported across epithelial membranes in the absence of any hydrostatic or osmotic gradients. A prime example is the small intestine, where 10 liters of water are absorbed each day. Although water absorption is secondary to active solute transport, the coupling mechanism between solute an …
1 de ene. de 2001 · For example, 1) the coupling coefficient for Na + and glucose transport is 2:1; 2) in the absence of sugar, Na + is transported with kinetics similar to those of Na +-glucose cotransport; i.e., two Na ions are transported per cycle; 3) the maximum rate of Na +-glucose cotransport at saturating membrane potentials is independent of sodium concentration; and 4) rapid voltage-jump experiments in ...
