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  1. Step 1, Obtain the entity of the training data. Step 2, Obtain a fine-grained dictionary. Use the jieba word segmentation tool to segment the entities of the training data obtained in the first step. After Remov-ing duplicate entities and deleting unreasonable segmentation results, we get a fine-grained dictionary.

  2. Encorafenib (LGX818) is a promising BRAF V600E inhibitor that has efficacy against metastatic melanoma. To better understand its pharmacokinetics, we studied its interactions with the multidrug efflux transporters ABCB1 and ABCG2 and the multidrug metabolizing enzyme CYP3A. In polarized MD …

  3. 1 de mar. de 2013 · L. Gan Novel microemulsion in situ electrolyte-triggered gelling system for ophthalmic delivery of lipophilic cyclosporine A: in vitro and in vivo results. Int. J. Pharm. (2009) J. Zhang et al. Topical use of Coenzyme Q(10)-loaded liposomes coated with trimethyl chitosan: tolerance, precorneal retention and anti-cataract effect.

  4. 17 de ene. de 2024 · Twisted bilayers of 2D semiconductors are being intensively investigated due to their emergent physical properties, but their controlled bottom-up synthesis remains challenging. Here, the authors ...

  5. Objectives: Current evidence suggests that microorganisms are associated with neoplastic diseases; however, the role of the airway microbiome in lung cancer remains unknown. To investigate the taxonomic profiles of the lower respiratory tract (LRT) microbiome in patients with lung cancer. Materials and methods: BALF samples were collected in a discovery set comprising 150 individuals ...

  6. 15 de ago. de 2020 · Ochratoxin A (OTA) is a dietary mycotoxin that can cause nephrotoxicity, hepatotoxicity, neurotoxicity and carcinogenicity. We found that in mice OTA is transported by the drug transporters mouse (m)ABCB1 and/or mABCG2, mOATP1A/1B, and human (h)OATP1B3. The complete deletion of mABCB1 and mABCG2 res …

  7. Carrier recombination mechanisms and efficiency droop in GaInN/GaN light-emitting diodes Qi Dai,1 Qifeng Shan,1 Jing Wang,1 Sameer Chhajed,1 Jaehee Cho,1 E. Fred Schubert,1,a Mary H. Crawford,2 Daniel D. Koleske,2 Min-Ho Kim,3 and Yongjo Park3 1Department of Physics, Applied Physics and Astronomy and Department of Electrical, Computer, and Systems Engineering, Rensselaer Polytechnic Institute ...