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  1. The available evidence suggests that use of ACE inhibitors and angiotensin 2 receptor antagonists or thiazide diuretics have the potential to reduce zinc levels in hypertensive patients. Additional research using larger participant numbers and accounting for dietary zinc intakes are required.

  2. Although the cause in some cases may be inadequate dietary intake of zinc, inhibitors of zinc absorption are most likely the most common causative factor. Phytate, which is present in staple foods like cereals, corn and rice, has a strong negative effect on zinc absorption from composite meals.

  3. 17 de feb. de 2024 · Introduction. Significance of zinc in human health. Zinc cannot be synthesised within the human body, so external intake of zinc is essential to maintain adequate levels in the body [ 1 ]. It is the second most abundant trace element in the body, after iron [ 2 ].

  4. 14 de feb. de 2023 · Benefits. Types. Dosage. Safety & side effects. Bottom line. Many people turn to zinc lozenges and supplements when they feel sick, and for good reason. It is one of the most abundant trace...

  5. Results: Eight eligible studies were identified which involved the use of ACE inhibitors, thiazide diuretics, beta blockers, or ARB drugs of which five included a control group Studies used urinary zinc excretion, plasma zinc levels or erythrocyte zinc as key measures of zinc status.

  6. 20 de mar. de 2018 · Collectively, these findings indicate captopril may lower zinc status and increase the risk of zinc deficiency, but only with chronic use at higher doses, or in individuals with hypertension and comorbidities. Specific ACE inhibitors may affect the occurrence or severity of zinc depletion differently.