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  1. Purpose of study. NWTS 1 – To determine the effect of surgical technique on the results of the treatment. NWTS 2 – To study the prognosis of patients with Wilms' tumor. NWTS 3 – To reduce the treatment for low-risk patients and find better chemotherapy for those at high risk for relapse.

  2. Dos grandes grupos cooperativos se han involucrado en el desarrollo e investigación del tumor de Wilms: el National Wilms Tumor Study Group (NWTSG) en Estados Unidos y la Sociedad Internacional de Oncología Pediátrica (SIOP) en Europa. Ambos difieren en el momento en que realizan la cirugía.

  3. Abstract. Since its inception in 1969, the NWTSG has performed successful studies that are now the model for the management of pediatric malignancies. Future studies may use genetic markers to stratify high-risk patients beyond the traditional staging system.

  4. 14 de oct. de 2021 · Wilms tumour (WT) is a childhood embryonal tumour that is paradigmatic of the intersection between disrupted organogenesis and tumorigenesis. Many WT genes play a critical (non-redundant) role in...

  5. 15 de may. de 2014 · Stepwise advances made by the National Wilms Tumor Study Group (NWTSG), which was succeeded by the Children's Oncology Group (COG) in 2002, and the International Society of Pediatric Oncology (SIOP) have resulted in overall survival rates of approximately 90%.

  6. 1 de abr. de 2021 · Two large collaborative groups – National Wilms Tumor Study Group (NWTSG)/Children's Oncology Group (COG) and The International Society of Paediatric Oncology (SIOP) have laid down the guidelines for standardized treatment of WT, though differing in the diagnostic and therapeutic approach.

  7. El tumor de Wilms es el tumor maligno primario del riñón más frecuente que se produce en los niños y corresponde al 5% de todos los tumores en este grupo de edad. Actualmente hay mayor prevalencia de esta enfermedad no necesariamente por incremento propio de la enfermedad,