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  1. 16 de oct. de 2023 · MCR has been proposed as a useful construct to identify older adults at high risk of developing dementia and mobility declines. This syndrome is particularly relevant to the concept of CF, as it ...

  2. Screening for Frailty in the Clinical Setting. Frailty is associated with greater prevalence of adverse health outcomes, including mortality, disability, worsening mobility, falls, and hospitalization in the US population 4, and is predictive of these outcomes in epidemiological cohorts 11,20.

  3. While the underlying mechanisms of cognitive frailty are still unclear, factors shown to be associated with cognitive frailty include sociodemographic factors, social status, nutritional status, geriatric syndrome, physical and cognitive activities, functional status, comorbidities, medication use, gut-derived metabolites and structural changes ...

  4. 4 de mar. de 2017 · The objective of the present narrative review was to examine clinical and epidemiological studies investigating the recently proposed construct of cognitive frailty and its subtypes, with a focus on operational definitions, clinical criteria, and emerging biomarkers potentially useful for the screening of this novel entity.

  5. 7 de mar. de 2019 · The new clinical and research AD criteria established by the National Institute on Aging-Alzheimer's Association and the American Psychiatric Association could improve the differential diagnosis of cognitive impairment within the cognitive frailty construct.

  6. 1 de mar. de 2019 · Screening instruments have often been used to determine objective cognitive decline. •. Lifespan trajectories should be taken into account in understanding cognitive frailty. •. A strong operational definition of cognitive frailty is necessary. •. Interventional studies are needed to establish the role of preventive strategies. Abstract. Objective.

  7. Early screening leads to better prevention and management of frailty, increasing the possibility of reversing it. Developing assessment tools by incorporating disease states of older adults using effective interventions has become the most effective approach for preventing and controlling frailty.