Resultado de búsqueda
7 de may. de 2024 · While clozapine is indicated in the management of treatment-resistant schizophrenia, it is associated with a considerable adverse drug reaction (ADR) burden, and not all patients achieve adequate symptomatic response.
20 de may. de 2024 · The critical treatment window of clozapine in treatment-resistant schizophrenia: secondary analysis of an observational study. Psychiatry Res. 2017;250:65-70. Wang G, Zheng W, Li XB, et al. ECT augmentation of clozapine for clozapine-resistant schizophrenia: a meta-analysis of randomized controlled trials.
Hace 5 días · 1 INTRODUCTION. Despite being the most effective antipsychotic medication for treatment-resistant psychosis (Siskind et al., 2016), clozapine is under-utilized and there are often long delays to its commencement when it is prescribed (Thien & O'Donoghue, 2019).This is despite compelling evidence that clozapine results in superior outcomes in a broad range of domains, such as remission of ...
Hace 4 días · Fleischhacker WW, Heikkinen ME, Olié JP, et al. Effects of adjunctive treatment with aripiprazole on body weight and clinical efficacy in schizophrenia patients treated with clozapine: a randomized, double-blind, placebo-controlled trial.
13 de may. de 2024 · The early utilization of clozapine in individuals resistant to other antipsychotics and in specific clinical scenarios, where clozapine has demonstrated efficacy, presents an opportunity for improvement and evolutionary stabilization for those individuals based on the clinical remission or recovery produced .
14 de may. de 2024 · Clozapine, renowned for its efficacy in treatment-resistant schizophrenia, is associated with rare yet potentially severe side effects, including hematological disorders, myocarditis, seizures and gastrointestinal obstruction.
Hace 5 días · Clozapine, which has a high affinity for serotonin receptors, has been shown to be more effective in treatment-resistant schizophrenia. Then, there is increased interest in the role of serotonin in pathogenesis and treatment of schizophrenia.
