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11 de feb. de 2022 · Bone marrow is a red, spongy material inside your bones that produces blood cells. The most common cause of aplastic anemia is from your immune system attacking the stem cells in your bone marrow. Other factors that can injure bone marrow and affect blood cell production include: Radiation and chemotherapy treatments.
Bone Marrow Aplasia is the disappearance of the cells responsible for blood production in the bone marrow. As a consequence, there is a decrease in red blood cells (RBC), white blood cells (WBC) and platelets in the peripheral blood. Medullary aplasia can be:
25 de oct. de 2018 · “Aplastic” refers to the failure of marrow to form blood, and hematopoietic failure is the end-organ effect of diverse pathophysiological mechanisms. Yet a seemingly “empty” bone marrow may...
22 de jun. de 2023 · Aplastic anemia is a rare but serious blood disorder. It happens when your bone marrow can’t make enough blood cells and platelets. People with aplastic anemia have an increased risk of serious infections, bleeding issues, heart issues and other complications.
The term aplastic anemia commonly implies a panhypoplasia of the bone marrow with cytopenias in at least two hematopoietic lineages. In contrast, pure red blood cell (RBC) aplasia is restricted to the erythroid cell line. Etiology of Aplastic Anemia.
Bone marrow aplasia refers to those hematologic conditions that are caused by a marked reduction and/or defect in the pluripotent or committed stem cells, or the failure of the bone marrow microenvironment to support hematopoiesis. The clinical outcome is anemia, leukopenia, and/or thrombocytopenia.
