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Editors: Pierre Hainaut, Klas G. Wiman. p53 is considered the most important cancer gene. p53 is a target for novel cancer therapy strategies already underway. p53 works as a sensor of oncogenic environmental stress. Written by world-leading scientists in the p53 field.
This book, written by world-leading p53 researchers including many of those who have shaped the field over the past 25 years, provides unique insights into the progress of the p53 field and the prospects for better cancer diagnosis and therapy the future.
From oncogene to tumour suppressor gene. The molecular cloning of the p53 cDNA (Zakut-Houri et al., 1985) allowed a variety of studies to increase our insight into the function of p53 in cell...
Reference functional assays and structural analysis: Given the huge diversity of cellular and animal models for wild-type or mutant p53 functions, it will be important to set up standard,...
p53 rose to the status of « superstar » among cancer-related genes, catching the essential lessons of 25 years of research to identify major paths towards applications.
18 de abr. de 2005 · This book, written by world-leading p53 researchers including many of those who have shaped the field over the past 25 years, provides unique insights into the progress of the field and the prospects for better cancer diagnosis and therapy in the future.
26 de oct. de 2007 · This book, written by world-leading p53 researchers including many of those who have shaped the field over the past 25 years, provides unique insights into the progress of the field and the prospects for better cancer diagnosis and therapy in the future.
