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The information in the Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer relates cytogenetic changes and their genomic consequences, in particular gene fusions, to tumor characteristics, based either on individual cases or associations.
11 de ene. de 2023 · Are you researching genomic abnormalities? Bioinformatician Deena Bleich gives an overview of the online tool, “Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer,” and how it can help you analyze genomic data.
Chromosome Abnormalities: Information about the genomic abnormalities of the clones and chromosomes. View by Genomic Coordinates: The calculated data of the genomic imbalances in a table, also downloadable in a .csv file.
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer (2017). Mitelman F, Johansson B and Mertens F (Eds.), http://cgap.nci.nih.gov/Chromosomes/Mitel man. Curation Activity 5 main tools. Online education materials. Filling Database Search Fields. https://cgap.nci.nih.gov/Chromosomes/Help.
30 de jul. de 2003 · Chromosome aberrations can be analyzed using an increasing number of efficient, large-scale genomic and molecular genetic technologies, such as analysis of chromosome banding...
26 de dic. de 2018 · Practically all balanced chromosome abnormalities in cancer that have been characterized at the molecular level have been shown to exert their effect through one of two mechanisms: deregulation, usually resulting in the overexpression of a seemingly normal gene in one of the breakpoints, or creation of a chimeric gene through the fusion of parts...
7 de may. de 2020 · Abstract. Blast crisis is one of the remaining challenges in chronic myeloid leukemia (CML). Whether additional chromosomal abnormalities (ACAs) enable an earlier recognition of imminent blastic...
