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  1. Ventilator-associated pneumonia (VAP) is the most frequent ICU-acquired infection. 1–3 It is associated with significant increases in the length of stay, healthcare costs and both crude and attributed mortality. 4–7 Therefore, potential functional, mechanical and pharmacological prevention measures of VAP have frequently been investigated ...

  2. Nosocomial pneumonia is a frequent infection that is classified into two groups [ 1 ]: HAP, which develops in hospitalised patients after 48 h of admission, and does not require (but may include) artificial ventilation at the time of diagnosis [ 2, 3 ]; and VAP, which occurs in intensive care unit (ICU) patients who have received mechanical vent...

  3. Among nosocomial pneumonias, ventilator-associated pneumonia (VAP) develops in intensive care unit (ICU) patients who have been mechanically ventilated for at least 48 h. Patients with severe nosocomial pneumonia who require mechanical ventilation during their treatment after the onset of infection do not meet the definition of VAP.

  4. 1. In patients with suspected VAP, we recommend including coverage for S. aureus, Pseudomonas aeruginosa, and other gram-negative bacilli in all empiric regimens (strong recom-mendation, low-quality evidence). i. We suggest including an agent active against MRSA for the empiric treatment of suspected VAP only in patients with

  5. 10 de mar. de 2020 · Ventilator-associated pneumonia (VAP) is one of the most frequent ICU-acquired infections. Reported incidences vary widely from 5 to 40% depending on the setting and diagnostic criteria. VAP is associated with prolonged duration of mechanical ventilation and ICU stay.

  6. Ventilator Associated Pneumonia (VAP) is defined as pneumonia occurring in a patient within 48 hours or more after intubation with an endotracheal tube or tracheostomy tube and which was not present before. Early onset VAP occurs within 48 hours and late onset VAP beyond 48 hours of tracheal intubation.

  7. For preventing VAP, a semi-recumbent position (i.e., elevation of the head of bed to 30–45°) has been extensively studied as a simple strategy for patients undergoing MV and is a recom-mendable measure in several clinical practice guidelines [8, 10–12].

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