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Hace 10 horas · Significantly more men develop amyotrophic lateral sclerosis (ALS) than women, and heritability is not uniform between male and female transmissions, together suggesting a role for sex in the genetic aetiology of the disease. We therefore performed sex-stratified genome-wide and transcriptome-wide analyses of ALS risk, identifying six novel sex-specific risk loci including MEF2C , which shows ...
Hace 10 horas · Alfred the Great (also spelled Ælfred; c. 849 – 26 October 899) was King of the West Saxons from 871 to 886, and King of the Anglo-Saxons from 886 until his death in 899. He was the youngest son of King Æthelwulf and his first wife Osburh, who both died when Alfred was young.Three of Alfred's brothers, Æthelbald, Æthelberht and Æthelred, reigned in turn before him.
Hace 10 horas · Desiderius Erasmus Roterodamus (/ ˌ d ɛ z ɪ ˈ d ɪər i ə s ɪ ˈ r æ z m ə s /; Dutch: [ˌdeːziˈdeːriʏs eˈrɑsmʏs]; English: Erasmus of Rotterdam or Erasmus; 28 October c.1466 – 12 July 1536) was a Dutch Christian humanist, Catholic theologian, educationalist, satirist, and philosopher.Through his vast number of translations, books, essays, prayers and letters, he is considered ...