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Hace 1 día · Normal function of the androgen receptor. Testosterone (T) enters the cell and, if 5-alpha-reductase is present, is converted into dihydrotestosterone (DHT). Upon steroid binding, the androgen receptor (AR) undergoes a conformational change and releases heat-shock proteins (hsps). Phosphorylation (P) occurs before or after steroid binding.
Hace 6 horas · Early life and education. Kelsey Grammer was born in Saint Thomas, U.S. Virgin Islands. Grammer's mother, Sally Cranmer (1928–2008), was a singer and actress. His father, Frank Allen Grammer Jr. was a musician, owned a restaurant called Greer's Place, and owned and edited the Virgin Islands View magazine. He had one younger sister, Karen, and four half-siblings from his father's second marriage.