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Hace 1 hora · Keloids, marked by abnormal cellular proliferation and excessive extracellular matrix (ECM) accumulation, pose significant therapeutic challenges. Ethyl pyruvate (EP), an inhibitor of the high-mobility group box 1 (HMGB1) and TGF-β1 pathways, has emerged as a potential anti-fibrotic agent. Our research evaluated EP’s effects on keloid fibroblast (KF) proliferation and ECM production ...
Hace 1 hora · May 28, 2024. In a Vivid Sydney exclusive, Golden Globe® and Emmy Award® winning actress and comedian, Amy Poehler has taken part in a special Vivid Ideas event at the Sydney Opera House on Monday 27 May. Poehler, who is one of Hollywood’s most versatile and sought-after talents, with credits including actress, writer, director, producer ...
