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  1. El término p21 se emplea para un gen humano localizado en el cromosoma 6 (ubicación 6p21.2), que codifica a un inhibidor de la cinasa dependiente de ciclina, el cual inhibe directamente la actividad de las enzimas de los complejos ciclina-CDK2 y ciclina-CDK4.

  2. In this review, we will focus on the multiple functions of p21 in cell cycle regulation, apoptosis and gene transcription after DNA damage and briefly discuss the pathways and factors that have critical roles in p21 expression and activity.

  3. www.p21online.com › Prophet21Prophet 21

    Learn how to access the ERP system with Prophet 21, a powerful and flexible solution for distributors.

  4. en.wikipedia.org › wiki › P21p21 - Wikipedia

    p21 is a potent cyclin-dependent kinase inhibitor (CKI). The p21 (CIP1/WAF1) protein binds to and inhibits the activity of cyclin-CDK2, -CDK1, and -CDK4 /6 complexes, and thus functions as a regulator of cell cycle progression at G 1 and S phase.

  5. 13 de jun. de 2014 · Averiguar por qué existe un porcentaje de personas (menos del uno por ciento) infectadas con el VIH pero que logran controlar la enfermedad —los llamados controladores de élite— ha sido y es uno de los objetivos de numerosas investigaciones para la “cura” de esta enfermedad.

  6. 1 de jun. de 2016 · The inhibitory effect of P21 on cell cycle progression correlates with its nuclear localization. P21 can be induced by both p53-dependent and p53-independent mechanisms. Some other important functions attributed to p21 include transcriptional regulation, modulation or inhibition of apoptosis.

  7. 14 de may. de 2009 · The cyclin-dependent kinase inhibitor p21 (also known as p21WAF1/Cip1) promotes cell cycle arrest in response to many stimuli.

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