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  1. 6 de mar. de 2019 · Approximately 40% of patients with aortic stenosis (AS) show discordant Doppler-echocardiographic parameters with aortic valve area (AVA) <1 cm2 and/or index iAVA <0.6 cm2/m2 (consistent with severe AS) and the mean gradient (MG) <40 mmHg, consistent with mild/moderate AS. Accurate diagnosis of true severe low flow low gradient AS versus pseudo-severe aortic stenosis is important for prognosis ...

  2. 31 de mar. de 2016 · Abstract. An important proportion of patients with aortic stenosis (AS) have a ‘low-gradient’ AS, i.e. a small aortic valve area (AVA <1.0 cm 2) consistent with severe AS but a low mean transvalvular gradient (<40 mmHg) consistent with non-severe AS.The management of this subset of patients is particularly challenging because the AVA-gradient discrepancy raises uncertainty about the actual ...

  3. 26 de jun. de 2015 · Abstract. Aortic stenosis (AS) occurs in almost 10% of adults over age 80 years with a mortality about 50% at 2 years unless outflow obstruction is relieved by aortic valve replacement (AVR). Development of AS is associated with anatomic, clinical and genetic risk factors including a bicuspid valve in 50%; clinical factors that include older ...

  4. www.uptodate.com › contents › indications-for-valve-replacement-for-high-gradientUpToDate

    INTRODUCTION. —. Aortic valve replacement (AVR) by surgical aortic valve replacement (SAVR) or transcatheter aortic valve implantation (TAVI) is the only effective treatment for severe aortic stenosis (AS) [ 1,2 ]. Indications for aortic valve replacement (by SAVR or TAVI) in adults with high gradient AS are discussed here.

  5. Aortic stenosis can be classified into 7 stages based on the valve's anatomy and hemodynamics as well as the patients symptoms. ... D3: Symptomatic severe low gradient with normal LVEF • Heart failure • Angina • Syncope or presyncope • Severe calcification with severely reduced leaflet motion

  6. Hace 2 días · Aortic stenosis is a narrowing of the aortic valve opening and can sometimes be referred to as a failing heart valve. Aortic stenosis restricts the blood flow from the left ventricle to the aorta may also affect the pressure in the left atrium. Although some people have aortic stenosis because of a congenital heart defect called a bicuspid ...

  7. The effect of calcification on aortic stenosis severity is largely affected by sex, ... (2023) Effects of vitamins K2 and D3 supplementation in patients with severe coronary artery calcification: a study protocol for a randomised controlled trial, BMJ Open, 10.1136/bmjopen-2023-073233, 13:7, (e073233), Online publication date: 1-Jul-2023. ...