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Heinz body anemia results from toxic effects of maple leaves, wild onions, phenothiazines, or methylene blue. Oxidative damage to erythrocytes leads to hemolytic anemia characterized by the presence of Heinz bodies and eccentrocytes on the blood smear. Maple leaf toxicity also leads to methemoglobinemia and brown discoloration of mucous ...
Corps de Heinz. Mis en évidence par des colorants vitaux basophiles, les corps de Heinz correspondent à de l' hémoglobine ( Hb) précipitée (chaînes bêta sans hème) visibles sous la forme d'une petite protubérance qui déforme le globule rouge. Ils se forment dans les agressions oxydatives de l'Hb et accompagnent souvent la formation de ...
15 de jun. de 1999 · This is a form of nonspherocytic hemolytic anemia of Dacie type I (in vitro autohemolysis is not corrected by added glucose). After splenectomy, which has little benefit, basophilic inclusions called Heinz bodies are demonstrable in the erythrocytes. Before splenectomy, diffuse or punctate basophilia may be evident. Most of these cases are probably instances of hemoglobinopathy. The hemoglobin ...
11 de dic. de 2017 · Morphology: dense round granules at the periphery of a red blood cell. Result from oxidant injury to red blood cells which causes hemoglobin to precipitate and form intracellular inclusions. Commonly seen with: eccentrocytes Clinical relevance: indicates oxidant injury to red blood cells. Oxidant injury may result from certain drugs (propofol ...
24 de jul. de 2023 · Learn about Heinz bodies, abnormal structures within red blood cells, and their implications for overall health. Discover the causes, associated conditions, diagnostic approaches, and management strategies related to Heinz body formation.
8 de feb. de 2014 · Abstract. Background: Many cases of severe neonatal hyperbilirubinemia never have the underlying cause of the jaundice clearly identified. Thus they are said to have ‘idiopathic' severe neonatal jaundice. However, finding the exact cause, if it is a genetic condition, can enable informed anticipatory guidance regarding future episodes of hemolysis, anemia, or bilirubin cholelithiasis ...
19 de jul. de 2021 · An overview of haemolytic anaemia including sub-types, clinical features (symptoms, signs), investigations and management options.
