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Atypical mitosis is considered a feature of malignancy, however, its significance in breast cancer (BC) remains elusive. Here, we aimed to assess the clinical value of atypical mitoses in BC and to explore their underlying molecular features. Atypical and typical mitotic figures were quantified and correlated with clinicopathological variables in a large cohort of primary BC tissue sections (n ...
19 de jun. de 2014 · Defects of mitosis result in various nuclear abnormalities, namely, micronuclei, binucleation, ... constitute an early step in the tumorigenic transformation of stem and progenitor cells and result in formation of atypical/multipolar mitosis (According to studies done by Arnold (1879), von Hansemann (1890), Mendelsohn).
As células eucarióticas, incluindo as do corpo humano, usam um processo chamado mitose para dividir e criar novas células. Uma mitose atípica é uma célula em divisão anormal. Como resultado desta divisão celular anormal, as células recém-criadas recebem uma quantidade desigual de material genético (DNA) e são incapazes de funcionar ...
MF, atypical mitotic figures (AMF) and mitotic like figures (MLF). A recent manuscript provides numerous images of each of these and provides details of how to correctly identify each.9 Mitosis or karyokinesis occurs during the M phase of the cell cycle. Mitosis is the
15 de ene. de 2021 · 病理人最熟悉不過的－有絲分裂 (Mitosis)有絲分裂常是判斷腫瘤及進行腫瘤病理分級的一個重要指標， 許多常見腫瘤，如：乳腺腫瘤、軟組織腫瘤、肥大細胞瘤、黑色素瘤等等，都需要仔細去數有絲分裂相，才能給予臨床最精確的病理分級 ， 是病理醫師們最熟悉但不是很愛見到的朋友😂我們都知道 ...
Atypische mitose. Eukaryote cellen, inclusief die in het menselijk lichaam, gebruiken een proces genaamd mitosis om te delen en nieuwe cellen te creëren. Een atypische mitose is een abnormaal delende cel. Als gevolg van deze abnormale celdeling ontvangen de nieuw aangemaakte cellen een ongelijke hoeveelheid genetisch materiaal (DNA) en kunnen ...
2 de may. de 2022 · Atypical mitosis is considered a feature of malignancy, however, its significance in breast cancer (BC) remains elusive. Here, we aimed to assess the clinical value of atypical mitoses in BC and to explore their underlying molecular features. Atypical and typical mitotic figures were quantified and correlated with clinicopathological variables ...
