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  1. Hace 4 horas · 2.1 Production of Hydroxyapatite, Functionalization and Tablets. Hydroxyapatite was obtained following this process: 1) fresh bovine bones (from femurs and tibias) were sawed in cylindrical pieces of 5–10 cm long; 2) the remaining soft tissues (tendons, muscles and fat) were cut with a sharp knife; 3) the pieces were immersed in boiling water during 4 h in order to lift off most adhered ...